10^th International Tissue Repair and Regeneration Congress

A low-cost injectable hydrogel that could help wounds heal faster Wound healing can be tough and challenging, especially when a patient has other health obstacles that seriously can delay the process. Often injectable hydrogels are applied to irregular shaped wounds, like diabetic ulcers to form a temporary matrix to keep the wound stable while cells undergoes repair and rejuvenation . The condition is that current hydrogels are not porous enough and do not allow neighboring cells to pass through toward the wound to help it repair. A specific solution was discovered to make hydrogels more porous which can help heal the wound faster.  The researchers made a macroporous hydrogel by combining readily available gelatin microgels. The hydrogels that are a few hundred microns in diameter with an inexpensive enzyme named microbial transglutaminase (mTG). Gelatin is a natural protein derived from collagen, a protein found in connective tissue in the body such as s...

Cardiac Regeneration strategies: Staying young at Heart The heart tissue of mammals has the limited capacity to regenerate after an injury such as a heart attack or cardiac injuries in part due to the inability to reactivate a cardiac muscle cell and proliferation. Generally injured hearts do not heal themselves. Cardiac muscle cells or cardiomyocytes do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Therefore, most people who had a severe heart attack or other injury related to the heart, will develop heart failure and that’s the leading reason of mortality from Heart Diseases. As we know that cell proliferation is much essential for the tissue regeneration and cardiomyocytes are highly specialized cells which involves in maintaining the pumping of heart. In previous findings it has been proved that the Hippo pathway stops the Proliferation of cardiomyocytes by inhibiting the activity of YAP pathway. For the reason, a mouse model was de...