10^th International Tissue Repair and Regeneration Congress

Minimize scarring in cosmetic surgery Human skin is a complex tissue that shows properties that arise primarily from the alignment of the collagen fibers in the upper dermis layer of the skin, ultimately causing skin tension lines. These lines are essential during surgery, as they are used to guide incisions that produce the least conspicuous scars. While there are many skin tension guidelines which helps surgeons make incisions that create invisible scars, skin anisotropy or the skin's property of having directionally dependent mechanical properties. Scientists have developed a new device that could help in minimise the scarring during or after surgery by ascertaining the orientation of skin tension lines, which is very much important for wound-healing after surgery. If we make incisions across the direction that collagen is aligned, the risk of keloid scar formation is increased but when we cut along the direction of the aligned collagen then wounds heals better ...

CAN STEM CELLS HELP WITH AGING? What is aging? Aging is a natural process. Over time, the cells of the body become damaged and die gradually. Dead cells are replaced too slowly to reimburse for this loss. The signs of aging are begin to appear along with health issues like impaired hearing and vision, loss of muscle strength and bone mass, decreased immunity and cognition, and inefficient metabolism. Aging cells contribute to disease. If aging in the cells can be prevented, slowed down or reversed, many diseases could be controlled or cured. Stem cell research and advanced regenerative medicine therapies are being looked at for providing solutions to many of life’s problems. What are Stem Cells? Stem cells have the ability to change, evolve, duplicate, and adapt into other types of cells the essence of body regeneration. Stem cells have the potential to develop into many cell types in our body. They generally lie dormant in bone marrow and fat stores. MSCs are the bes...

Best foods for Wound Healing Our body requires nutrients from a variety of healthy foods in order to heal wounds effectively. What we eat is one of the key factors that determine how quickly our body will heal. Eating foods that are high in protein for wound healing has long-term benefits as every cell in the human body contains protein. Scientific research has disclosed a great insight into food that can delay wound-healing and how certain foods containing proteins, nutrients and vitamins can speed up wound healing . Eating protein-rich foods is one of the best things that we can do to help heal our wounds. Below is some best protein rich food that promotes wound healing. 1.   Nuts : Like beans, legumes & nuts are an excellent source of protein. Cashews, Peanuts, and almonds all have high amounts of protein. We can snack on nuts throughout the day to enhance the wound-healing process. It’s a healthier habit than turning to chips or fast foods when we are craving a...

Why we need to Stop Vaping before Surgery The health hazards of smoking have been recorded for decades, but the research on vaping the smoking of electronic cigarettes, is still in its infancy. It’s the nicotine in cigarettes, which leads to the habit of smoking and poor healing, anaesthesia risks and a host of other potential complications for a surgery patient.  Electronic cigarettes often are characterized as a safer alternative to traditional tobacco products but vaping liquid contains nicotine, which significantly increases the risk for complications related to surgery and anaesthesia. Nicotine tightens blood vessels and decreases healthy circulation of blood, which delays healing and can lead to poor scarring, infection and other dangerous complications. Nicotine starves healing tissues of critical blood supply: Nicotine acts as a vasoconstrictor; it shrinks the blood vessels and decreases healthy circulation of blood, which is very much essential for ti...

A low-cost injectable hydrogel that could help wounds heal faster Wound healing can be tough and challenging, especially when a patient has other health obstacles that seriously can delay the process. Often injectable hydrogels are applied to irregular shaped wounds, like diabetic ulcers to form a temporary matrix to keep the wound stable while cells undergoes repair and rejuvenation . The condition is that current hydrogels are not porous enough and do not allow neighboring cells to pass through toward the wound to help it repair. A specific solution was discovered to make hydrogels more porous which can help heal the wound faster.  The researchers made a macroporous hydrogel by combining readily available gelatin microgels. The hydrogels that are a few hundred microns in diameter with an inexpensive enzyme named microbial transglutaminase (mTG). Gelatin is a natural protein derived from collagen, a protein found in connective tissue in the body such as s...

Cardiac Regeneration strategies: Staying young at Heart The heart tissue of mammals has the limited capacity to regenerate after an injury such as a heart attack or cardiac injuries in part due to the inability to reactivate a cardiac muscle cell and proliferation. Generally injured hearts do not heal themselves. Cardiac muscle cells or cardiomyocytes do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Therefore, most people who had a severe heart attack or other injury related to the heart, will develop heart failure and that’s the leading reason of mortality from Heart Diseases. As we know that cell proliferation is much essential for the tissue regeneration and cardiomyocytes are highly specialized cells which involves in maintaining the pumping of heart. In previous findings it has been proved that the Hippo pathway stops the Proliferation of cardiomyocytes by inhibiting the activity of YAP pathway. For the reason, a mouse model was de...

Mesenchymal Stem Cells plays a vital role in  Wound Repair It has been scientifically proven that stem cells play a crucial role in tissue renewal and regeneration. Mesenchymal stem cells (MSCs) are those parts of the most important population of adult stem cells which helps in Repair and Regeneration of tissue. MSCs have been isolated from various sites like connective tissues, such as adipose tissue, muscle, placenta, umbilical cord matrix, blood, liver, and dental pulp. Bone marrow. MSCs also act as a therapeutic agent for regenerative medicine, immune disorders, cancer, and gene therapy. Mesenchymal stems cells (MSCs) are frequently found in bone marrow and they play a vital role in repair of damaged organs. The transformation of a single MSC into complex tissue like bone and cartilage, then starts with its association with other MSCs in order to form microscopic clusters via a process called as condensation. Wound healing requires a coordinated interaction...